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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2
All Species:
45.45
Human Site:
Y236
Identified Species:
62.5
UniProt:
P24941
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24941
NP_001789.2
298
33930
Y236
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Chimpanzee
Pan troglodytes
XP_523720
325
36841
Y256
G
V
T
Q
L
P
D
Y
K
G
S
F
P
K
W
Rhesus Macaque
Macaca mulatta
XP_001113345
298
33812
Y236
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Dog
Lupus familis
XP_856049
298
33839
Y236
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Cat
Felis silvestris
Mouse
Mus musculus
P97377
346
38960
Y284
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Rat
Rattus norvegicus
Q63699
298
33869
Y236
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
Y237
D
V
E
S
L
Q
D
Y
K
N
T
F
P
K
W
Frog
Xenopus laevis
P23437
297
33852
Y236
G
V
T
T
M
P
D
Y
K
S
T
F
P
K
W
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
Y236
G
V
T
S
M
P
D
Y
K
P
S
F
P
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
F239
G
V
T
Q
L
P
D
F
K
T
K
F
P
R
W
Honey Bee
Apis mellifera
XP_393450
299
34033
Y235
G
V
S
Q
L
R
D
Y
T
S
M
F
P
R
W
Nematode Worm
Caenorhab. elegans
P34556
332
38277
Y255
G
V
E
S
L
P
D
Y
K
A
T
F
P
K
W
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
Y236
G
V
T
S
L
P
D
Y
K
T
S
F
P
R
W
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
G230
P
N
E
D
T
W
P
G
V
T
S
L
P
D
F
Maize
Zea mays
P23111
294
33816
G230
P
N
E
Q
S
W
P
G
V
S
C
L
P
D
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
G230
P
Y
E
D
T
W
R
G
V
T
S
L
P
D
Y
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
P237
T
P
N
E
A
I
W
P
D
I
V
Y
L
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.8
99.6
98.9
N.A.
85.2
98.6
N.A.
N.A.
65.3
88.9
90.2
N.A.
62.7
69.9
56.9
75.9
Protein Similarity:
100
79.6
99.6
99.6
N.A.
85.8
99.6
N.A.
N.A.
77.8
94.9
94.9
N.A.
74.8
82.2
69.8
88.6
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
N.A.
60
80
100
N.A.
60
46.6
73.3
80
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
73.3
93.3
100
N.A.
80
66.6
86.6
93.3
Percent
Protein Identity:
66.4
66.7
N.A.
67.1
62.4
N.A.
Protein Similarity:
83.2
82.2
N.A.
81.5
79.1
N.A.
P-Site Identity:
13.3
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
20
13.3
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% C
% Asp:
6
0
0
12
0
0
77
0
6
0
0
0
0
18
6
% D
% Glu:
0
0
30
6
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
77
0
0
12
% F
% Gly:
71
0
0
0
0
0
0
18
0
6
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
0
0
6
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
71
0
6
0
0
59
0
% K
% Leu:
0
0
0
0
36
0
0
0
0
0
0
18
6
0
0
% L
% Met:
0
0
0
0
42
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
12
6
0
0
0
0
0
0
6
0
0
0
0
0
% N
% Pro:
18
6
0
0
0
65
12
6
0
36
0
0
95
6
0
% P
% Gln:
0
0
0
24
0
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
6
0
0
0
0
0
0
18
0
% R
% Ser:
0
0
6
53
6
0
0
0
0
18
59
0
0
0
0
% S
% Thr:
6
0
59
6
12
0
0
0
6
24
18
0
0
0
0
% T
% Val:
0
77
0
0
0
0
0
0
18
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
18
6
0
0
0
0
0
0
0
77
% W
% Tyr:
0
6
0
0
0
0
0
71
0
0
0
6
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _